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  • Scale-up of Capsule Filling Operations Using a Nozzle-Dosator Machine
    Scale-up of Capsule Filling Operations Using a Nozzle-Dosator Machine
    This paper discusses the methodology for the development and scale up of capsule filling operations using a research capsule filling unit (Labby,MG2) and an industrial capsule filling machine (Planeta,MG2).
    2019-06-12
  • Manufacturing of Low Fill Weight Capsules Using a Nozzle Dosator Capsule Filling Machine
    Manufacturing of Low Fill Weight Capsules Using a Nozzle Dosator Capsule Filling Machine
    Capsule filling using nozzle dosators (ND) has been widely investigated (Jones, 2001; Newton, 2012) and it is one of the main technologies used by pharmaceutical industry today. Nozzles come in sizes that match the diameter of capsules (from 00 to 5), and deliver a specific volume of powder into capsules. However, the amount of powder that the smallest nozzle (size 5) can handle is in the range of 40 mg-80 mg (depending on the density of the powder formulation).
    2019-06-11